Optimal Ligand Descriptor for Pocket Recognition Based on the Beta-Shape

نویسندگان
چکیده

برای دانلود رایگان متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Optimal Ligand Descriptor for Pocket Recognition Based on the Beta-Shape

Structure-based virtual screening is one of the most important and common computational methods for the identification of predicted hit at the beginning of drug discovery. Pocket recognition and definition is frequently a prerequisite of structure-based virtual screening, reducing the search space of the predicted protein-ligand complex. In this paper, we present an optimal ligand shape descrip...

متن کامل

Dtw-Radon-Based Shape Descriptor for Pattern Recognition

In this paper, we present a pattern recognition method that uses dynamic programming (DP) for the alignment of Radon features. The key characteristic of the method is to use dynamic time warping (DTW) to match corresponding pairs of the Radon features for all possible projections. Thanks to DTW, we avoid compressing the feature matrix into a single vector which would otherwise miss information....

متن کامل

Shape Descriptor using Polar Plot for Shape Recognition

This paper presents my work on computing shape models that are computationally fast and invariant to basic transformations like translation, scaling and rotation. In this paper, I propose shape detection using a feature called shape context. Shape context describes all boundary points of a shape with respect to any single boundary point. Thus it is descriptive of the shape of the object. Object...

متن کامل

A Shape Descriptor Based on Trainable COSFIRE Filters for the Recognition of Handwritten Digits

The recognition of handwritten digits is an application which has been used as a benchmark for comparing shape recognition methods. We train COSFIRE filters to be selective for different parts of handwritten digits. In analogy with the neurophysiological concept of population coding we use the responses of multiple COSFIRE filters as a shape descriptor of a handwritten digit. We demonstrate the...

متن کامل

Template Based Shape Descriptor

We introduce a new 3D shape descriptor which maps the surface features onto an arbitrary template surface using mean-value interpolation. A compact numerical shape descriptor is extracted using manifold harmonics on the template. We show that mean-value interpolation is a strong alternative to the often used projection. The utility of using different templates is established by showing that con...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

ژورنال

عنوان ژورنال: PLOS ONE

سال: 2015

ISSN: 1932-6203

DOI: 10.1371/journal.pone.0122787